junosand (mark) submitted a FOX Sports article with tips on how to win your NCAA Tournament pool. There's a ton of them, here's a few:

Don't pick the No. 16 seeds

If you're desperate, try for a No. 15 seed to make a big splash. Four of them have won first-round games;

Pick at least one No. 3 or No. 4 seed to lose: There have only been three times in the last 21 seasons that a No. 3 or 4 seed did not go down in the first round.

There's too many more to go through here, but it's not too late to change your bracket so get on it!